Nanozyme：A-Pd@MoO3-xNH
| 【Numbering】BKMA104020 | 【CAS】CAS | ||
| 【Item No.】BKMA104020-2 | 【specification】 | ||
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Name: A-Pd @ MoO3-xNH
Composition: Pd, MoO3-x
Particle size: 100 nm
Application: triple-negative breast cancer treatment
Storage conditions: -4℃
Other instructions: the shelf life of half a year in the sealed state [main advantages] 1. Using the irregular shape characteristics of nanoPd, A-Pd @ MoO3-xNH nanoenzyme simultaneously exposed the Pd (111) crystal surface with catalase activity and Pd (100) crystal surface with oxidase activity, forming the dual active center. This can catalyze the cascade enzyme reaction, and further enrich the cytotoxic superoxide radicals (O2) while overcoming the tumor anaerobic; 2. Based on the redox reaction, nanoenzymes can effectively degrade GSH that consumes O2 and avoid the negative effects of GSH. More importantly, the molybdenum oxide (MoO3-x) acts as a reversible electron transfer station to receive electrons on the crystal surface of Pd (111) through an oxygen bridge and a small amount of Mo-Pd bonds, and then transfer to the crystal surface of Pd (100).
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Composition: Pd, MoO3-x
Particle size: 100 nm
Application: triple-negative breast cancer treatment
Storage conditions: -4℃
Other instructions: the shelf life of half a year in the sealed state [main advantages] 1. Using the irregular shape characteristics of nanoPd, A-Pd @ MoO3-xNH nanoenzyme simultaneously exposed the Pd (111) crystal surface with catalase activity and Pd (100) crystal surface with oxidase activity, forming the dual active center. This can catalyze the cascade enzyme reaction, and further enrich the cytotoxic superoxide radicals (O2) while overcoming the tumor anaerobic; 2. Based on the redox reaction, nanoenzymes can effectively degrade GSH that consumes O2 and avoid the negative effects of GSH. More importantly, the molybdenum oxide (MoO3-x) acts as a reversible electron transfer station to receive electrons on the crystal surface of Pd (111) through an oxygen bridge and a small amount of Mo-Pd bonds, and then transfer to the crystal surface of Pd (100).
Title:Dual Active Centers Linked by a Reversible Electron Station as a Multifunctional Nanozyme to Induce Synergetically Enhanced Cascade Catalysis for Tumor-Specific Therapy
Article link:https://mp.weixin.qq.com/s?src=11×tamp=1688722586&ver=4636&signature=9f*PQpFHcUByWhFdndeXnZR9HSF*fIWS2XHF8kKn1KFaqHhUyZ5xHx6Y9brevxnXbkIVKz3rpqm1b2T6exxIyfODslYV3WADZPFTjsd1IJ0UY2cM29bieCDFEfRdUPVK&new=1| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance |
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| Warm tips: Suzhou Beike nano products are only used for scientific research, not for human body,different batches of products have different specifications and performance.The website pictures are from the Internet. The pictures are for reference only. Please take the real object as the standard. In case of infringement, please contact us to delete them immediately. |
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